TargetMol

Charantin

Product Code:
 
TAR-T10786
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T10786-5mg5mgEnquire
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Further Information

Bioactivity:
Charantin is a steroidal saponin isolated from Momordica charantia. It increases the release of insulin and slowing down gluconeogenesis. Charantin can inhibit GSK-3.
CAS:
57126-62-2
Formula:
C105H178O18
Molecular Weight:
1728.561
Pathway:
PI3K/Akt/mTOR signaling; Stem Cells
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.[H][C@@]12CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.[H][C@@]12CC[C@H]([C@H](C)CC[C@@H](CC)C(C)=C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Target:
GSK-3

References

1. Wang HY, et al. Differential anti-diabetic effects and mechanism of action of charantin-rich extract of Taiwanese Momordica charantia between type 1 and type 2 diabetic mice. Food Chem Toxicol. 2014 Jul;69:347-56.