CMLD012072

TargetMol
Product Code: TAR-T10847
Supplier: TargetMol
CodeSizePrice
TAR-T10847-5mg5mg£850.00
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Quantity:
TAR-T10847-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T10847-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.
CAS:
2368900-33-6
Formula:
C32H32N2O7
Molecular Weight:
556.615
Purity:
0.98
SMILES:
COC(=O)[C@@H]1[C@@H](c2ccccc2)[C@@]2(Oc3cc(OC)cc(OC)c3[C@@]22NC(=N[C@@]12O)C1CC1)c1ccc(OC)cc1

References

1. Chu J, et al. Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors. Cell Chem Biol. 2019 Nov 21;26(11):1586-1593.