Cobimetinib (R-enantiomer)

TargetMol
Product Code: TAR-T10856
Supplier: TargetMol
CodeSizePrice
TAR-T10856-5mg5mg£1,099.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor.
CAS:
934660-94-3
Formula:
C21H21F3IN3O2
Molecular Weight:
531.318
Purity:
0.98
SMILES:
OC1(CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F)[C@H]1CCCCN1

References

1. Hoeflich KP, et al. Intermittent administration of MEK inhibitor GDC-0973 plus PI3K inhibitor GDC-0941 triggers robust apoptosis and tumor growth inhibition. Cancer Res. 2012 Jan 1;72(1):210-9.