TargetMol

Cyclobuxine D

Product Code:
 
TAR-T10913
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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TAR-T10913-5mg5mgEnquire
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Further Information

Bioactivity:
Cyclobuxine D is a steroidal alkaloid extracted from Buxus microphylla. Cyclostatin D has obvious bradycardia effect on rat heart, and inhibits acetylcholine and Ba ++ induced longitudinal muscle contraction isolated from rabbit jejunum.
CAS:
2241-90-9
Formula:
C25H42N2O
Molecular Weight:
386.624
Purity:
0.98
SMILES:
[H][C@]1([C@H](C)NC)[C@H](O)C[C@@]2(C)[C@]3([H])CC[C@@]4([H])C(=C)[C@H](CC[C@@]44C[C@@]34CC[C@]12C)NC

References

1. . A. Eshonov, et al. Alkaloids of Buxus sempervirens, Crystal and Molecular Structure of Cyclobuxine-D and Imperialine. Chemistry of Natural Compounds. 12 January 2014. 49:11791182. 2. Kwon, Jun-Tack, et al. Effects of Cyclobuxine D on Drug-Induced Contractions of the Isolated Rat Uterine Muscle and Potassium-Activated Calcium Channels in an Intestinal Smooth Muscle. The Korean Journal of Pharmacology. 1988. 24 (1): 103-109.