DHODH-IN-11

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TargetMol
Product Code: TAR-T11020
Supplier: TargetMol
CodeSizePrice
TAR-T11020-1mg1mg£103.00
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Quantity:
TAR-T11020-1mL1 mL * 10 mM (in DMSO)£146.00
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Quantity:
TAR-T11020-5mg5mg£148.00
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Quantity:
TAR-T11020-10mg10mg£201.00
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Quantity:
TAR-T11020-25mg25mg£319.00
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Quantity:
TAR-T11020-50mg50mg£442.00
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Quantity:
TAR-T11020-100mg100mg£616.00
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TAR-T11020-500mg500mg£1,219.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.
CAS:
1263303-95-2
Formula:
C15H11N3O2
Molecular Weight:
265.272
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Purity:
0.9984
SMILES:
ON=C(/C#N)C(=O)Nc1ccc(cc1)-c1ccccc1
Target:
Dehydrogenase; DNA/RNA Synthesis

References

1. Giorgis M, et al. 1,2,5-Oxadiazole analogues of leflunomide and related compounds. Eur J Med Chem. 2011 Jan;46(1):383-92.