Dihydrocytochalasin B
| Code | Size | Price |
|---|
| TAR-T11042-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Dihydrocytochalasin B (H2CB) is a cell division inhibitor that changes the morphology of cells, similar to cytochalasin B. Does not inhibit glucose transport. Dihydrocytochalasin B (H2CB) disrupts the structure of actin and inhibits the ability of growth factors to stimulate DNA synthesis, reversibly preventing the initiation of DNA synthesis. Dihydrorelaxin B (H2CB) inhibits active calcium transport and causes an increase in calcium ions in mucosal scrape.
CAS:
39156-67-7
Formula:
C29H39NO5
Molecular Weight:
481.633
Purity:
0.98
SMILES:
[H][C@]12[C@H](Cc3ccccc3)NC(=O)[C@]11OC(=O)CC[C@H](O)CCC[C@@H](C)CC=C[C@@]1([H])[C@H](O)C(=C)[C@H]2C
References
1. Atlas SJ, et al. Dihydrocytochalasin B. Biological effects and binding to 3T3 cells. J Cell Biol. 1978 Feb;76(2):360-70.
2. Jande SS, et al. Effects of cytochalasin B and dihydrocytochalasin B on calcium transport by intestinal absorptive cells. Calcif Tissue Int. 1981;33(2):143-51.
3. Maness PF, et al. Dihydrocytochalasin B disorganizes actin cytoarchitecture and inhibits initiation of DNA synthesis in 3T3 cells. Cell. 1982 Aug;30(1):253-62.