Dacarbazine citrate

TargetMol
Product Code: TAR-T1120L2
Supplier: TargetMol
CodeSizePrice
TAR-T1120L2-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1120L2-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1120L2-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Dacarbazine citrate is an alkylating agent used to treat cancers of the lymphatic system and malignant melanoma (a type of skin cancer) in patients with certain conditions: islet cell carcinoma (part of the pancreas) Soft tissue sarcoma (cancer of muscles, tendons, blood vessels carrying blood or lymph, joints, and fat).
CAS:
64038-56-8
Formula:
C12H18N6O8
Molecular Weight:
374.31
Purity:
0.98
SMILES:
CN(C)N=Nc1[nH]cnc1C(N)=O.OC(=O)CC(O)(CC(O)=O)C(O)=O

References

1. Di Martino A, Sedlarik V. Amphiphilic chitosan-grafted-functionalized polylactic acid based nanoparticles as a delivery system for doxorubicin and temozolomide co-therapy. Int J Pharm. 2014 Oct 20;474(1-2):134-45. doi: 10.1016/j.ijpharm.2014.08.014. Epub 2014 Aug 12. PubMed PMID: 25124059. 2. Stark P, Steinmetz A, Hefetz M, Hardoff R. Misleading Ga-67 uptake in a patient with Hodgkin's disease, mediastinal deviation, and pulmonary compression. Clin Nucl Med. 2002 Dec;27(12):898-9. PubMed PMID: 12607876. 3. St-Coeur PD, Poitras JJ, Cuperlovic-Culf M, Touaibia M, Morin P Jr. Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics. J Neurooncol. 2015 Oct;125(1):91-102. doi: 10.1007/s11060-015-1899-6. Epub 2015 Aug 28. PubMed PMID: 26311249. 4. Buesa JM, Gracia M, Valle M, Estrada E, Hidalgo OF, Lacave AJ. Phase I trial of intermittent high-dose dacarbazine. Cancer Treat Rep. 1984 Mar;68(3):499-504. PubMed PMID: 6704980.