Fluxametamide

TargetMol
Product Code: TAR-T11307
Supplier: TargetMol
CodeSizePrice
TAR-T11307-1mg1mg£103.00
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TAR-T11307-5mg5mg£148.00
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TAR-T11307-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T11307-10mg10mg£195.00
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TAR-T11307-25mg25mg£306.00
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TAR-T11307-50mg50mg£503.00
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TAR-T11307-100mg100mg£687.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- and glutamate-gated chloride channels(IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls).
CAS:
928783-29-3
Formula:
C20H16Cl2F3N3O3
Molecular Weight:
474.26
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.9983
SMILES:
CONC=NC(=O)c1ccc(cc1C)C1=NOC(C1)(c1cc(Cl)cc(Cl)c1)C(F)(F)F
Target:
GABA Receptor

References

1. MihoAsahi, et al. Fluxametamide: A novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels. Pesticide Biochemistry and Physiology. 2. Wang K, Li B, Yu Y, et al. Bacterial Rdl2 dsRNA increased the insecticidal activity of GABAR blockers and allosteric modulators against Plutella xylostella[J]. bioRxiv. 2021