TargetMol

Fluxametamide

Product Code:
 
TAR-T11307
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T11307-1mg1mg£103.00
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TAR-T11307-5mg5mg£148.00
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TAR-T11307-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T11307-10mg10mg£195.00
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TAR-T11307-25mg25mg£306.00
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TAR-T11307-50mg50mg£503.00
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TAR-T11307-100mg100mg£687.00
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This product comes from: United States.
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Further Information

Bioactivity:
Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- and glutamate-gated chloride channels(IC50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls).
CAS:
928783-29-3
Formula:
C20H16Cl2F3N3O3
Molecular Weight:
474.26
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.9983
SMILES:
CONC=NC(=O)c1ccc(cc1C)C1=NOC(C1)(c1cc(Cl)cc(Cl)c1)C(F)(F)F
Target:
GABA Receptor

References

1. MihoAsahi, et al. Fluxametamide: A novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels. Pesticide Biochemistry and Physiology. 2. Wang K, Li B, Yu Y, et al. Bacterial Rdl2 dsRNA increased the insecticidal activity of GABAR blockers and allosteric modulators against Plutella xylostella[J]. bioRxiv. 2021