Fulvene-5
| Code | Size | Price |
|---|
| TAR-T11333-5mg | 5mg | £1,167.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Fulvene-5 has antitumor activity.Fulvene-5 is a potent NADPH oxidase 4 (NOX4) inhibitor with antioxidant properties. Fulvene-5 is a reactive oxygen species (ROS) modifying agent and a potent radioprotector.
CAS:
1075723-01-1
Formula:
C26H18N2
Molecular Weight:
358.444
Purity:
0.98
SMILES:
C1=CC(C=C1)=c1c2ccccc2[nH]c1=c1[nH]c2ccccc2c1=C1C=CC=C1
References
1. Murley JS, et al. ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response. Free Radic Biol Med. 2018 Aug 1;123:39-52.
2. Bhandarkar SS, et al. Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice. J Clin Invest. 2009 Aug;119(8):2359-65.
3. Weyemi U, et al. Inactivation of NADPH oxidases NOX4 and NOX5 protects human primary fibroblasts from ionizing radiation-induced DNA damage. Radiat Res. 2015 Mar;183(3):262-70.