GNE 220 Hydrochloride (1199590-75-4 free base)

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TargetMol
Product Code: TAR-T11443L
Supplier: TargetMol
CodeSizePrice
TAR-T11443L-100mg100mgEnquire
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TAR-T11443L-50mg50mgEnquire
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TAR-T11443L-5mg5mg£532.00
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TAR-T11443L-1mL1 mL * 10 mM (in DMSO)£578.00
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TAR-T11443L-10mg10mg£920.00
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TAR-T11443L-25mg25mg£1,909.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
GNE 220 Hydrochloride is a potent and selective inhibitor of MAP4K4 (IC50: 7 nM).
CAS:
T11443L
Formula:
C25H27ClN8
Molecular Weight:
474.99
Purity:
0.98
SMILES:
CN1N=CC(C2=NC(C)=C(NC3=NC=C(C4=CC=C(N5CCN(C)CC5)C=C4)C=C36)C6=N2)=C1.Cl

References

1. Vitorino P, et al. MAP4K4 regulates integrin-FERM binding to control endothelial cell motility. Nature. 2015 Mar 26;519(7544):425-30.