Phenoxybenzamine
| Code | Size | Price |
|---|
| TAR-T1158L-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Phenoxybenzamine is an α-1 adrenergic receptor antagonist. Phenoxybenzamine may exert a neuroprotective effect by reducing neuroinflammation after traumatic brain injury.
CAS:
59-96-1
Formula:
C18H22ClNO
Molecular Weight:
303.83
Purity:
0.98
SMILES:
CC(N(CCCl)CC1=CC=CC=C1)COC2=CC=CC=C2
References
1. van der Zee PA, de Boer A. Pheochromocytoma: a review on preoperative treatment with phenoxybenzamine or doxazosin. Neth J Med. 2014 May;72(4):190-201. Review. PubMed PMID: 24829175.
2. National Toxicology Program. Phenoxybenzamine hydrochloride. Rep Carcinog. 2011;12:344-5. PubMed PMID: 21863081.
3. Rau TF, Kothiwal A, Rova A, Rhoderick JF, Poulsen DJ. Phenoxybenzamine is neuroprotective in a rat model of severe traumatic brain injury. Int J Mol Sci. 2014 Jan 20;15(1):1402-17. doi: 10.3390/ijms15011402. PubMed PMID: 24447929; PubMed Central PMCID: PMC3907876.
4. Lin XB, Jiang L, Ding MH, Chen ZH, Bao Y, Chen Y, Sun W, Zhang CR, Hu HK, Cai Z, Lu CY, Zhou JY, Qian J, Wu XJ, Jin WL, Hu GH. Anti-tumor activity of phenoxybenzamine hydrochloride on malignant glioma cells. Tumour Biol. 2016 Mar;37(3):2901-8. doi: 10.1007/s13277-015-4102-y. Epub 2015 Sep 26. PubMed PMID: 26409450.