TargetMol

PI3K/mTOR Inhibitor-1

Product Code:
 
TAR-T12460
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12460-5mg5mg£1,171.00
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Quantity:
TAR-T12460-50mg50mg£2,303.00
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Quantity:
TAR-T12460-100mg100mg£3,042.00
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This product comes from: United States.
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Further Information

Bioactivity:
PI3K/mTOR Inhibitor-1 is a potent, orally bioavailable dual inhibitor of PI3K/mTOR (PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ/mTOR with IC50s of 20/376/204/46/186 nM)
CAS:
1949802-49-6
Formula:
C18H22FN5O3S
Molecular Weight:
407.46
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
C[C@H]1COCCN1c1nc(cc(n1)C1(CC1)S(C)(=O)=O)-c1cnc(N)cc1F
Target:
PI3K

References

1. Shen S, et al. Discovery of an Orally Bioavailable Dual PI3K/mTOR Inhibitor Based on Sulfonyl-Substituted Morpholinopyrimidines. ACS Med Chem Lett. 2018 Jun 25;9(7):719-724.