PNRI-299
| Code | Size | Price |
|---|
| TAR-T12508-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).
CAS:
550368-41-7
Formula:
C21H15N5O4
Molecular Weight:
401.382
Purity:
0.98
SMILES:
O=C(NCc1ccccc1)C1=CC(=O)Cn2n1c(=O)n(-c1cccc(c1)C#N)c2=O
References
1. Nguyen C, et al. Chemogenomic identification of Ref-1/AP-1 as a therapeutic target for asthma. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1169-73.
2. Souza DG, et al. NF-kappaB plays a major role during the systemic and local acute inflammatory response following intestinal reperfusion injury. Br J Pharmacol. 2005 May;145(2):246-54.