PrPSc-IN-1
Code | Size | Price |
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TAR-T12563-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation(IC50 of 1.6 μM), with anti-prion activity.
CAS:
1315475-30-9
Formula:
C22H17N5O
Molecular Weight:
367.412
Purity:
0.98
SMILES:
COc1ccc2c(c1)nc(NN=Cc1ccnc3ccccc13)c1cccn21
References
1. Zaccagnini L, et al. Identification of novel fluorescent probes preventing PrPSc replication in prion diseases. Eur J Med Chem. 2017 Feb 15;127:859-873.