PSI-7409
Code | Size | Price |
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TAR-T12572-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).
CAS:
1015073-42-3
Formula:
C10H16FN2O14P3
Molecular Weight:
500.158
Purity:
0.98
SMILES:
C[C@@]1(F)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O
References
1. Lam AM, et al. PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication. Antimicrob Agents Chemother. 2010 Aug;54(8):3187-96.
2. Murakami E, et al. Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977.