(R)-(+)-Anatabine
| Code | Size | Price |
|---|
| TAR-T12636-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.
CAS:
126454-22-6
Formula:
C10H12N2
Molecular Weight:
160.22
Purity:
0.98
SMILES:
C1N[C@H](CC=C1)c1cccnc1
References
1. Jothi L. Nallasivam, et al. Synthetic modifications of bifunctional homoallylamines: Synthesis of 2-arylpiperidines, (R)-anatabine and (R)-anabasine. An International Journal for Rapid Communication of Synthetic Organic Chemistry. Volume 49, 2019-Issue 21: 2815-2822.
2. Paris D, et al. Anatabine lowers Alzheimer's A? production in vitro and in vivo. Eur J Pharmacol. 2011 Nov 30;670(2-3):384-91.
3. Xing H, et al. A Pharmacological Comparison of Two Isomeric Nicotinic Receptor Agonists: The Marine Toxin Isoanatabine and the Tobacco Alkaloid Anatabine. Mar Drugs. 2020 Feb 11;18(2). pii: E106.
4. eo EJ, et al. Phytochemicals as inhibitors of NF-?B for treatment of Alzheimer's disease. Pharmacol Res. 2018 Mar;129:262-273.