TargetMol

T-448 free base

Product Code:
 
TAR-T13056
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13056-5mg5mg£1,010.00
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Quantity:
TAR-T13056-50mg50mg£1,982.00
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Quantity:
TAR-T13056-100mg100mg£2,560.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
T-448 free base is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM).
CAS:
1597426-52-2
Formula:
C17H20N4OS
Molecular Weight:
328.43
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
Cc1nnc(NC(=O)c2cccc(c2)[C@@H]2C[C@H]2NC2CCC2)s1
Target:
Histone Demethylase

References

1. Matsuda S, et al. T-448, a specific inhibitor of LSD1 enzyme activity, improves learning function without causing thrombocytopenia in mice. Neuropsychopharmacology. 2018 Dec 22.