TargetMol

T-448

Product Code:
 
TAR-T13057
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13057-5mg5mg£724.00
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TAR-T13057-50mg50mg£2,143.00
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Quantity:
TAR-T13057-100mg100mg£2,801.00
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This product comes from: United States.
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Further Information

Bioactivity:
T-448 is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM).
CAS:
1597426-53-3
Formula:
C17H20N4OS.1/2C4H4O4
Molecular Weight:
386.5
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
O=C(NC1=NN=C(C)S1)C2=CC=CC([C@H]3[C@H](NC4CCC4)C3)=C2.O=C(O)/C=C/C(O)=O.[1/2]
Target:
Histone Demethylase

References

1. Matsuda S, et al. T-448, a specific inhibitor of LSD1 enzyme activity, improves learning function without causing thrombocytopenia in mice. Neuropsychopharmacology. 2018 Dec 22.