TargetMol

T-705RTP

Product Code:
 
TAR-T13075
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T13075-100mg100mgEnquire
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TAR-T13075-50mg50mgEnquire
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TAR-T13075-5mg5mgEnquire
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
T-705RTP is a selective and GTP-competitive of influenza virus RNA polymerase(IC50 of 0.14 μM and a Ki of 1.52 μM), has potent anti-influenza virus activity.
CAS:
740790-94-7
Formula:
C10H15FN3O15P3
Molecular Weight:
529.156
Purity:
0.98
SMILES:
NC(=O)c1nc(F)cn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c1=O

References

1. Furuta Y, et al. Mechanism of action of T-705 against influenza virus. Antimicrob Agents Chemother. 2005 Mar;49(3):981-6. 2. Sangawa H, et al. Mechanism of action of T-705 ribosyl triphosphate against influenza virus RNA polymerase. Antimicrob Agents Chemother. 2013 Nov;57(11):5202-8.