TP-472
Code | Size | Price |
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TAR-T13190-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T13190-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).
CAS:
2079895-62-6
Formula:
C20H19N3O2
Molecular Weight:
333.391
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
CC(=O)c1cc(-c2cc(ccc2C)C(=O)NC2CC2)c2ncccn12
Target:
Epigenetic Reader Domain
References
1. Moustakim M, et al. Chemical probes and inhibitors of bromodomains outside the BET family. Medchemcomm. 2016 Dec 7;7(12):2246-2264.
2. Gatchalian J, et al. A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells. Nat Commun. 2018 Dec 3;9(1):5139.