Cytochalasin C

TargetMol
Product Code: TAR-T13630
Supplier: TargetMol
CodeSizePrice
TAR-T13630-5mg5mg£766.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Cytochalasin C is a cell-permeable fungal toxin that can induce the formation of nuclear sticks. Cytochalasin C is 10 times less toxic than cytochalasin D in mice.
CAS:
22144-76-9
Formula:
C30H37NO6
Molecular Weight:
507.627
Purity:
0.98
SMILES:
[H][C@]12[C@H](Cc3ccccc3)NC(=O)[C@]11[C@H](OC(C)=O)C=C[C@@](C)(O)C(=O)[C@@H](C)CC=C[C@@]1([H])[C@H](O)C(C)=C2C

References

1. Foissner I, et al. Wide-ranging effects of eight cytochalasins and latrunculin A and B on intracellular motility and actin filament reorganization in characean internodal cells. Plant Cell Physiol. 2007 Apr;48(4):585-97. 2. Yahara I, et al. Correlation between effects of 24 different cytochalasins on cellular structures and cellular eventsand those on actin in vitro. J Cell Biol. 1982 Jan;92(1):69-78. 3. Trendowski M, et al. Tolerated doses in zebrafish of cytochalasins and jasplakinolide for comparison with tolerateddoses in mice in the evaluation of pre-clinical activity of microfilament-directed agents in tumormodel systems in vivo. In Vivo. 2014 Nov-Dec;28(6):1021-31.