SMARCA-BD ligand 1 for Protac dihydrochloride

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TargetMol
Product Code: TAR-T13890
Supplier: TargetMol
CodeSizePrice
TAR-T13890-1mg1mg£131.00
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TAR-T13890-5mg5mg£222.00
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TAR-T13890-10mg10mg£309.00
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TAR-T13890-25mg25mg£550.00
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TAR-T13890-50mg50mg£755.00
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TAR-T13890-100mg100mg£1,010.00
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TAR-T13890-500mg500mg£1,958.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
CAS:
2369053-68-7
Formula:
C14H19Cl2N5O
Molecular Weight:
344.24
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
Cl.Cl.Nc1nnc(cc1N1CCNCC1)-c1ccccc1O
Target:
Epigenetic Reader Domain

References

1. Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.