15-Acetoxyscirpenol
Code | Size | Price |
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TAR-T14003-5mg | 5mg | £871.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
15-acetoxyscirpenol is one of acetoxyscirpenol moiety mycotoxins (ASMs), showed strongly induces apoptosis and inhibits Jurkat T cell growth in a dose-dependent manner by activating other caspases independent of caspase-3[1].
CAS:
2623-22-5
Formula:
C17H24O5
Molecular Weight:
308.374
Pathway:
Apoptosis; Proteases/Proteasome
Purity:
0.98
SMILES:
CC(=O)OC[C@]12CCC(C)=C[C@H]1O[C@@H]1[C@H](O)C[C@@]2(C)[C@]11CO1
Target:
Caspase
References
1. Lee DH, et al. Induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving PARP in Jurkat T cells through treatment with acetoxyscirpenol mycotoxins. Biol Pharm Bull. 2006 Apr;29(4):648-54.