Dehydroaltenusin
| Code | Size | Price |
|---|
| TAR-T15094-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Dehydroaltenusin is a selective eukaryotic DNA polymerase α inhibitor and a type of antibiotic produced by a fungus (IC50: 0.68 μM). Dehydroaltenusin inhibits mammalian pol α activity.
CAS:
31186-13-7
Formula:
C15H12O6
Molecular Weight:
288.255
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
COc1cc(O)c2C(=O)O[C@@]3(C)C=C(O)C(=O)C=C3c2c1
Target:
DNA/RNA Synthesis
References
1. Mizushina Y, et al. Dehydroaltenusin is a specific inhibitor of mammalian DNA polymerase ?. Expert Opin Investig Drugs. 2011 Nov;20(11):1523-34.