Etoricoxib HCl
| Code | Size | Price |
|---|
| TAR-T1574L-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Etoricoxib HCl is a synthetic, nonsteroidal anti-inflammatory drug. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2, resulting in inhibition of the conversion of arachidonic acid into prostaglandins.
CAS:
202409-40-3
Formula:
C18H16Cl2N2O2S
Molecular Weight:
395.3
Purity:
0.98
SMILES:
Cl.Cc1ccc(cn1)-c1ncc(Cl)cc1-c1ccc(cc1)S(C)(=O)=O
References
1. Clarke R, Derry S, Moore RA. Single dose oral etoricoxib for acute postoperative pain in adults. Cochrane Database Syst Rev. 2014 May 8;5:CD004309. doi: 10.1002/14651858.CD004309.pub4. Review. PubMed PMID: 24809657.
2. Lories RJ. Etoricoxib and the treatment of ankylosing spondylitis. Expert Opin Drug Metab Toxicol. 2012 Dec;8(12):1599-608. doi: 10.1517/17425255.2012.741120. Epub 2012 Nov 6. Review. PubMed PMID: 23126318.
3. Clarke R, Derry S, Moore RA. Single dose oral etoricoxib for acute postoperative pain in adults. Cochrane Database Syst Rev. 2012 Apr 18;4:CD004309. doi: 10.1002/14651858.CD004309.pub3. Review. Update in: Cochrane Database Syst Rev. 2014;5:CD004309. PubMed PMID: 22513922.
4. Alekseeva LI. [Comparative evaluation of the safety and efficacy of etoricoxib and diclofenac on the upper gastrointestinal tract in patients with osteoarthrosis and rheumatoid arthritis (the multinational etoricoxib and diclofenac arthritis long-term (MEDAL) study program)]. Ter Arkh. 2010;82(8):57-62. Review. Russian. PubMed PMID: 20873248.