ML418

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TargetMol
Product Code: TAR-T16110
Supplier: TargetMol
CodeSizePrice
TAR-T16110-1mg1mg£115.00
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TAR-T16110-5mg5mg£172.00
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Quantity:
TAR-T16110-10mg10mg£230.00
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Quantity:
TAR-T16110-25mg25mg£350.00
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Quantity:
TAR-T16110-50mg50mg£497.00
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Quantity:
TAR-T16110-100mg100mg£687.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.
CAS:
1928763-08-9
Formula:
C19H24ClN3O3
Molecular Weight:
377.87
Pathway:
Membrane transporter/Ion channel
Purity:
0.981
SMILES:
CC(C)OC(=O)NC1CCN(Cc2cc(Cl)c3cccnc3c2O)CC1
Target:
Potassium Channel

References

1. ML418, et al. ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels. ACS Chem Neurosci. 2016 Jul 20;7(7):1013-23.