PhiKan 083

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TargetMol
Product Code: TAR-T16523L
Supplier: TargetMol
CodeSizePrice
TAR-T16523L-5mg5mg£122.00
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Quantity:
TAR-T16523L-1mL1 mL * 10 mM (in DMSO)£126.00
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Quantity:
TAR-T16523L-10mg10mg£161.00
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Quantity:
TAR-T16523L-25mg25mg£269.00
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Quantity:
TAR-T16523L-50mg50mg£366.00
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Quantity:
TAR-T16523L-100mg100mg£507.00
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Quantity:
TAR-T16523L-500mg500mg£1,002.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
PhiKan 083 is a carbazole derivative
CAS:
880813-36-5
Formula:
C16H18N2
Molecular Weight:
238.334
Pathway:
Apoptosis
Purity:
0.982
SMILES:
CCn1c2ccccc2c2cc(CNC)ccc12
Target:
Mdm2

References

1. Paulmurugan R, et al. A protein folding molecular imaging biosensor monitors the effects of drugs that restore mutant p53 structure and its downstream function in glioblastoma cells. Oncotarget. 2018 Apr 20;9(30):21495-21511. 2. Boeckler FM, et al. Targeted rescue of a destabilized mutant of p53 by an in silico screened drug. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10360-5. 3. Rauf SM, et al. Effect of Y220C mutation on p53 and its rescue mechanism: a computer chemistry approach. Protein J. 2013 Jan;32(1):68-74.