U-46619
| Code | Size | Price |
|---|
| TAR-T17189-1mg | 1mg | £464.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T17189-5mg | 5mg | £1,089.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
U-46619 is a stable analog of thromboxane A2 and acts as an effective TXA2 agonist.
CAS:
56985-40-1
Formula:
C21H34O4
Molecular Weight:
350.499
Pathway:
DNA Damage/DNA Repair|Others|Metabolism
Purity:
0.98
SMILES:
[H][C@]12CO[C@]([H])(C1)[C@H](C=C[C@@H](O)CCCCC)[C@H]2CC=C/CCCC(O)=O
Target:
Progesterone Receptor|PPAR
References
Su L, et al. The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways. Stem Cell Res Ther. 2018;9(1):313.
Schirner M, et al. U 46619 induces different blood pressure effects in male and female spontaneously hypertensive rats (SHR). Prostaglandins Leukot Essent Fatty Acids. 1993;48(6):469-473.
Ohkubo S,et al. Thromboxane A2-mediated shape change: independent of Gq-phospholipase C--Ca2+ pathway in rabbit platelets. Br J Pharmacol. 1996;117(6):1095-1104.