Amfenac
| Code | Size | Price |
|---|
| TAR-T1720L-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Amfenac promotes apoptosis in ARPE-19 cell culture.
CAS:
51579-82-9
Formula:
C15H13NO3
Molecular Weight:
255.273
Purity:
0.98
SMILES:
Nc1c(CC(O)=O)cccc1C(=O)c1ccccc1
References
1. Argun M, T?k L, U?uz AC, ?elik ?, T?k ?Y, Naziro?lu M. Melatonin and amfenac modulate calcium entry, apoptosis, and oxidative stress in ARPE-19 cell culture exposed to blue light irradiation (405 nm). Eye (Lond). 2014 Jun;28(6):752-60. doi: 10.1038/eye.2014.50. Epub 2014 Mar 7. PubMed PMID: 24603419; PubMed Central PMCID: PMC4058615.
2. Chastain JE, Sanders ME, Curtis MA, Chemuturi NV, Gadd ME, Kapin MA, Markwardt KL, Dahlin DC. Distribution of topical ocular nepafenac and its active metabolite amfenac to the posterior segment of the eye. Exp Eye Res. 2016 Apr;145:58-67. doi: 10.1016/j.exer.2015.10.009. Epub 2015 Oct 22. PubMed PMID: 26474497.
3. Yanni SE, Clark ML, Yang R, Bingaman DP, Penn JS. The effects of nepafenac and amfenac on retinal angiogenesis. Brain Res Bull. 2010 Feb 15;81(2-3):310-9. doi: 10.1016/j.brainresbull.2009.10.018. Epub 2009 Nov 6. PubMed PMID: 19897019; PubMed Central PMCID: PMC2815002.
4. Hiranuma T, Kato S, Hachisu M. Analgesic action of amfenac Na, a non-steroidal anti-inflammatory agent. J Pharmacobiodyn. 1988 Sep;11(9):612-9. PubMed PMID: 3265150.