SCR7 pyrazine

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TargetMol
Product Code: TAR-T1724
Supplier: TargetMol
CodeSizePrice
TAR-T1724-1mg1mg£97.00
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TAR-T1724-2mg2mg£107.00
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TAR-T1724-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T1724-5mg5mg£128.00
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TAR-T1724-10mg10mg£169.00
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TAR-T1724-25mg25mg£288.00
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TAR-T1724-50mg50mg£438.00
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TAR-T1724-100mg100mg£611.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).
CAS:
14892-97-8
Formula:
C18H12N4OS
Molecular Weight:
332.38
Pathway:
Apoptosis; DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.9985
SMILES:
Sc1nc2nc(-c3ccccc3)c(nc2c(=O)[nH]1)-c1ccccc1
Target:
Apoptosis; DNA/RNA Synthesis; CRISPR/Cas9

References

1. Srivastava M, et al. Cell. 2012, 151(7), 1474-1487. 2. Chu VT, et al. Nat Biotechnol. 2015, doi: 10.1038/nbt.3198.