MHY1485

TargetMol
Product Code: TAR-T1908
Supplier: TargetMol
CodeSizePrice
TAR-T1908-5mg5mg£105.00
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TAR-T1908-1mL1 mL * 10 mM (in DMSO)£109.00
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Quantity:
TAR-T1908-10mg10mg£119.00
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Quantity:
TAR-T1908-25mg25mg£161.00
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Quantity:
TAR-T1908-50mg50mg£228.00
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Quantity:
TAR-T1908-100mg100mg£362.00
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Quantity:
TAR-T1908-200mg200mg£500.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
MHY1485 is a mTOR activator. It inhibits the autophagic process by inhibition of fusion between autophagosomes and lysosomes, leading to the accumulation of LC3II protein and enlarged autophagosomes.
CAS:
326914-06-1
Formula:
C17H21N7O4
Molecular Weight:
387.4
Pathway:
PI3K/Akt/mTOR signaling; Autophagy
Purity:
0.98
SMILES:
[O-][N+](=O)c1ccc(Nc2nc(nc(n2)N2CCOCC2)N2CCOCC2)cc1
Target:
mTOR; Autophagy

References

1. Choi YJ, et al. PLoS One. 2012, 7(8), e43418. 2. Cheng Y, et al. PLoS One.2015, 10(2), e0117769.