Afegostat
Code | Size | Price |
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TAR-T19181-5mg | 5mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Afegostat is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
CAS:
169105-89-9
Formula:
C6H13NO3
Molecular Weight:
147.174
Purity:
0.98
SMILES:
OC[C@H]1CNC[C@@H](O)[C@@H]1O
References
1. Richter F, et al. A GCase chaperone improves motor function in a mouse model of synucleinopathy. Neurotherapeutics. 2014 Oct;11(4):840-56.