Calcitetrol
| Code | Size | Price |
|---|
| TAR-T19225-5mg | 5mg | £1,026.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Calcitetrol is the hormonally active form of vitamin D with three hydroxyl groups.
CAS:
72203-93-1
Formula:
C27H44O4
Molecular Weight:
432.645
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H]([C@H](C)CCC(O)C(C)(C)O)[C@@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C
References
1. Johanna A. Huhtakangas, Christopher J. Olivera, June E. Bishop et al. The Vitamin D Receptor Is Present in Caveolae-Enriched Plasma Membranes and Binds 1?,25(OH)2-Vitamin D3in Vivo and in Vitro. Molecular Endocrinology November 1, 2004 vol. 18 no. 11 2660
2. Robert A. Parise, Merrill J. Egorin, Beatriz Kanterewicz et al. CYP24, the enzyme that catabolizes the antiproliferative agent vitamin D, is increased in lung cancer. International Journal of Cancer. Volume 119, Issue 8, pages 1819-1828, 15 October 2006
3. Akiyoshi-Shibata M, Sakaki T, Ohyama Y, Noshiro M, Okuda K, Yabusaki Y. Further oxidation of hydroxycalcidiol by calcidiol 24-hydroxylase. A study with the mature enzyme expressed in Escherichia coli. Eur J Biochem. 1994 Sep 1;224(2):335-43.
4. Sonoko Masuda, Valarie Byford, Alice Arabian et al. Altered Pharmacokinetics of 1?,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3 in the Blood and Tissues of the 25-Hydroxyvitamin D-24-Hydroxylase (Cyp24a1) Null Mouse. Endocrinology February 1, 2005 vol.