DMH-1

TargetMol
Product Code: TAR-T1942
Supplier: TargetMol
CodeSizePrice
TAR-T1942-5mg5mg£113.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1942-1mL1 mL * 10 mM (in DMSO)£121.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1942-10mg10mg£138.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1942-25mg25mg£201.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1942-50mg50mg£304.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1942-100mg100mg£436.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1942-500mg500mg£863.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
DMH-1 is a potent and selective BMP inhibitor.
CAS:
1206711-16-1
Formula:
C24H20N4O
Molecular Weight:
380.451
Pathway:
Autophagy; Tyrosine Kinase/Adaptors; Stem Cells; Angiogenesis
Purity:
0.9992
SMILES:
CC(C)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12
Target:
ALK; Autophagy; TGF-beta/Smad

References

1. Hao J, et al. ACS Chem Biol. 2010, 5(2), 245-253. 2. Cross EE, et al. ACS Chem Biol. 2011, 6(9), 952-961. 3. Ao A, et al. PLoS One. 2012, 7(7), e41627. 4. Hao J, et al. PLoS One. 2014, 9(3), e90748. 6. Hover LD, et al. Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth. Cancer Lett. 2015 Nov 1;368(1):79-87. 7. Eixarch H, Calvo-Barreiro L, Costa C, et al. Inhibition of the BMP Signaling Pathway Ameliorated Established Clinical Symptoms of Experimental Autoimmune Encephalomyelitis[J]. Neurotherapeutics. 2020: 1-16.