TargetMol

Amastatin hydrochloride

Product Code:
 
TAR-T19665
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T19665-5mg5mg£850.00
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Further Information

Bioactivity:
Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.
CAS:
100938-10-1
Formula:
C21H39ClN4O8
Molecular Weight:
511.01
Purity:
0.98
SMILES:
Cl.CC(C)C[C@@H](N)[C@H](O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O

References

1. Kawabata A, Kinoshita M, Nishikawa H, Kuroda R, Nishida M, Araki H, Arizono N, Oda Y, Kakehi K. The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection. J Clin Invest. 2001 Jun;107(11):1443-50. PubMed PMID: 11390426; PubMed Central PMCID: PMC209315. 2. Kawabata A, Oono Y, Yonezawa D, Hiramatsu K, Inoi N, Sekiguchi F, Honjo M, Hirofuchi M, Kanke T, Ishiwata H. 2-Furoyl-LIGRL-NH2, a potent agonist for proteinase-activated receptor-2, as a gastric mucosal cytoprotective agent in mice. Br J Pharmacol. 2005 Jan;144(2):212-9. PubMed PMID: 15655521; PubMed Central PMCID: PMC1575994. 3. Gee NS, Kenny AJ. Proteins of the kidney microvillar membrane. Enzymic and molecular properties of aminopeptidase W. Biochem J. 1987 Aug 15;246(1):97-102. PubMed PMID: 2890346; PubMed Central PMCID: PMC1148244. 4. Kawabata A, Nishikawa H, Saitoh H, Nakaya Y, Hiramatsu K, Kubo S, Nishida M, Kawao N, Kuroda R, Sekiguchi F, Kinoshita M, Kakehi K, Arizono N, Yamagishi H, Kawai K. A protective role of protease-activated receptor 1 in rat gastric mucosa. Gastroenterology. 2004 Jan;126(1):208-19. PubMed PMID: 14699501.