Perthane
Code | Size | Price |
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TAR-T19737-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Perthane is the diethyl derivative of common pesticide DDD. It may cause adrenocortical atrophy in humans,and also prevent the formation of spontaneous mammary carcinoma.
CAS:
72-56-0
Formula:
C18H20Cl2
Molecular Weight:
307.26
Purity:
0.98
SMILES:
CCc1ccc(cc1)C(C(Cl)Cl)c1ccc(CC)cc1
References
1. Reuber MD. Histopathology of carcinomas of the liver in mice fed perthane. Tumori. 1980 Jun 30;66(3):277-83. PubMed PMID: 6255646.
2. LEONE LA, HAHN HB Jr, MELLETTE SJ. Studies of the effect of perthane on spontaneous and transplanted mammary carcinoma in the C3H mouse. Cancer Res. 1958 Nov;18(10):1161-6. PubMed PMID: 13596957.
3. TALIAFERRO I, LEONE L. Inhibitory effect of perthane (2,2-bis-[para-ethyl-phenyl]-1,1-dichloroethane) on adrenocortical function in human subjects. N Engl J Med. 1957 Oct 31;257(18):855-60. PubMed PMID: 13477401.
4. FINNEGAN JK, HENNIGAR GR, SMITH RB Jr, LARSON PS, HAAG HB. Acute and chronic toxicity studies on 2,2-bis-(p-ethylphenyl)-1,1-dichloroethane (perthane). Arch Int Pharmacodyn Ther. 1955 Oct 15;103(4):404-18. PubMed PMID: 13283630.