Diethyl bipy55'DC
Code | Size | Price |
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TAR-T19773-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Diethyl bipy55'DC inhibits CP4H activity in cultured cells. The stability of collagen relies on post-translational modifications, the most prevalent being the hydroxylation of collagen strands by collagen prolyl 4-hydroxylases.
CAS:
1762-46-5
Formula:
C16H16N2O4
Molecular Weight:
300.314
Purity:
0.98
SMILES:
CCOC(=O)c1ccc(nc1)-c1ccc(cn1)C(=O)OCC
References
1. Vasta JD, Andersen KA, Deck KM, Nizzi CP, Eisenstein RS, Raines RT. Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. ACS chemical biology. 2016;11(1):193-199. doi:10.1021/acschembio.5b00749.