TargetMol

D-Erythrose

Product Code:
 
TAR-T19828
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
D-Erythrose is an antitumor compound. D-Erythrose inhibits tumor growth in mice. D-erythrose significantly reduced the weight of the intraperitoneal tumor by 69.1%, markedly inhibited the development of ascites, and increased tumor cell apoptosis. D-erythrose possesses antitumor activity against colon cancer.
CAS:
583-50-6
Formula:
C4H8O4
Molecular Weight:
120.104
Purity:
0.98
SMILES:
OC[C@@H](O)[C@@H](O)C=O

References

1. Sousa CE, Ribeiro AM, Gil Fortes A, Cerqueira NM, Alves MJ. Total Facial Discrimination of 1,3-Dipolar Cycloadditions in a d-Erythrose 1,3-Dioxane Template: Computational Studies of a Concerted Mechanism. J Org Chem. 2017 Jan 20;82(2):982-991. doi: 10.1021/acs.joc.6b02518. Epub 2017 Jan 9. PubMed PMID: 28032997. 2. Szczepaniak M, Moc J. Anomerization reaction of bare and microhydrated d-erythrose via explicitly correlated coupled cluster approach. Two water molecules are optimal. J Comput Chem. 2017 Feb 15;38(5):288-303. doi: 10.1002/jcc.24680. Epub 2016 Nov 29. PubMed PMID: 27896831. 3. Kaufmann M, M?gge C, Kroh LW. Theory of the milieu dependent isomerisation dynamics of reducing sugars applied to d-erythrose. Carbohydr Res. 2015 Dec 11;418:89-97. doi: 10.1016/j.carres.2015.10.010. Epub 2015 Oct 30. PubMed PMID: 26580710. 4. Liu LL, Yi T, Zhao X. Antitumor effect of D-erythrose in an abdominal metastatic model of colon carcinoma. Oncol Lett. 2015 Feb;9(2):769-773. Epub 2014 Dec 3. PubMed PMID: 25621049; PubMed Central PMCID: PMC4301512.