TargetMol

Acriflavine Hydrochloride

Product Code:
 
TAR-T19832
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19832-500mg500mg£103.00
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Quantity:
TAR-T19832-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Acriflavine Hydrochloride is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.
CAS:
8063-24-9
Formula:
C14H14ClN3
Molecular Weight:
259.74
Pathway:
Chromatin/Epigenetic; Angiogenesis
Purity:
0.98
SMILES:
[Cl-].C[n+]1c2cc(N)ccc2cc2ccc(N)cc12
Target:
HIF

References

1. Deus D, Krischek C, Pfeifer Y, Sharifi AR, Fiegen U, Reich F, Klein G, Kehrenberg C. Comparative analysis of the susceptibility to biocides and heavy metals of extended-spectrum ?-lactamase-producing Escherichia coli isolates of human and avian origin, Germany. Diagn Microbiol Infect Dis. 2017 May;88(1):88-92. doi: 10.1016/j.diagmicrobio.2017.01.023. Epub 2017 Feb 8. PubMed PMID: 28256291. 2. Keys AL, Hitchins AD, Smiley RD. Contribution of Selective Conditions to Microbial Competition in Four Listeria Selective Enrichment Formulations. J Food Prot. 2016 Nov;79(11):1904-1910. doi: 10.4315/0362-028X.JFP-16-216. PubMed PMID: 28221922; PubMed Central PMCID: PMC5510592. 3. Chang TP, Leff DR, Shousha S, Hadjiminas DJ, Ramakrishnan R, Hughes MR, Yang GZ, Darzi A. Imaging breast cancer morphology using probe-based confocal laser endomicroscopy: towards a real-time intraoperative imaging tool for cavity scanning. Breast Cancer Res Treat. 2015 Sep;153(2):299-310. doi: 10.1007/s10549-015-3543-8. Epub 2015 Aug 18. PubMed PMID: 26283299. 4. Manivannan C, Meenakshi Sundaram K, Sundararaman M, Renganathan R. Investigation on the inclusion and toxicity of acriflavine with cyclodextrins: a spectroscopic approach. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Mar 25;122:164-70. doi: 10.1016/j.saa.2013.11.012. Epub 2013 Nov 13. PubMed PMID: 24309178.