Cirsilineol
| Code | Size | Price |
|---|
| TAR-T19886-5mg | 5mg | £1,050.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Cirsilineol is a compound isolated from the herb of Artemisia vestita Wall. Cirsilineol has been found to cause the induction of apoptosis via the mitochondrial pathway and activate anti-proliferative activity against cancer cells.
CAS:
41365-32-6
Formula:
C18H16O7
Molecular Weight:
344.319
Pathway:
Apoptosis|Neuroscience|Stem Cells|JAK/STAT signaling|Immunology/Inflammation
Purity:
0.98
SMILES:
COc1cc(ccc1O)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1
Target:
COX|Apoptosis|STAT
References
1. Polato?lu K, Karako? OC, Demirci F, G?k?e A, G?ren N. Chemistry and biological activities of Tanacetum chiliophyllum var. oligocephalum extracts. J AOAC Int. 2013 Nov-Dec;96(6):1222-7. PubMed PMID: 24645497.
2. Sheng X, Sun Y, Yin Y, Chen T, Xu Q. Cirsilineol inhibits proliferation of cancer cells by inducing apoptosis via mitochondrial pathway. J Pharm Pharmacol. 2008 Nov;60(11):1523-9. doi: 10.1211/jpp/60.11.0014. PubMed PMID: 18957174.
3. Hajd? Z, Hohmann J, Forgo P, M?th? I, Moln?r J, Zupk? I. Antiproliferative activity of Artemisia asiatica extract and its constituents on human tumor cell lines. Planta Med. 2014 Dec;80(18):1692-7. doi: 10.1055/s-0034-1383146. Epub 2014 Oct 8. PubMed PMID: 25295671.
4. Hammoud L, Seghiri R, Benayache S, Mosset P, Lobstein A, Chaabi M, Le?n F, Brouard I, Bermejo J, Benayache F. A new flavonoid and other constituents from Centaurea nicaeensis All. var. walliana M. Nat Prod Res. 2012;26(3):203-8. doi: 10.1080/14786419.2010.534995. Epub 2011 Aug 4. PubMed PMID: 21815723.