Rescinnamine
| Code | Size | Price |
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| TAR-T19911-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Rescinnamine is an inhibitor of angiotensin-converting enzyme. It also is a vinca alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia. It used as an antihypertensive drug.
CAS:
24815-24-5
Formula:
C35H42N2O9
Molecular Weight:
634.726
Purity:
0.98
SMILES:
COC1C(CC2CN3CCc4c([nH]c5cc(OC)ccc45)C3CC2C1C(=O)OC)OC(=O)C=Cc1cc(OC)c(OC)c(OC)c1
References
1. Wiens B, De Luca V. Molecular and biochemical characterization of a benzenoid/phenylpropanoid meta/para-O-methyltransferase from Rauwolfia serpentina roots. Phytochemistry. 2016 Dec;132:5-15. doi: 10.1016/j.phytochem.2016.10.004. Epub 2016 Oct 19. PubMed PMID: 27771009.
2. Fadaeinasab M, Basiri A, Kia Y, Karimian H, Ali HM, Murugaiyah V. New Indole Alkaloids from the Bark of Rauvolfia Reflexa and their Cholinesterase Inhibitory Activity. Cell Physiol Biochem. 2015;37(5):1997-2011. doi: 10.1159/000438560. Epub 2015 Nov 20. PubMed PMID: 26584298.
3. Iqbal M, Alam A, Wani TA, Khalil NY. Simultaneous determination of reserpine, rescinnamine, and yohimbine in human plasma by ultraperformance liquid chromatography tandem mass spectrometry. J Anal Methods Chem. 2013;2013:940861. doi: 10.1155/2013/940861. Epub 2013 Dec 5. PubMed PMID: 24383039; PubMed Central PMCID: PMC3870115.
4. AbdelHafez EM, Diamanduros A, Negureanu L, Luy Y, Bean JH, Zielke K, Crowe B, Vasilyeva A, Clodfelter JE, Aly OM, Abuo-Rahma GE, Scarpinato KD, Salsbury FR Jr, King SB. Computational and synthetic studies towards improving rescinnamine as an inducer of MSH2-dependent apoptosis in cancer treatment. Mol Cancer Biol. 2013;1(1). pii: 44. PubMed PMID: 25485184; PubMed Central PMCID: PMC4254817.