Elastatinal
| Code | Size | Price |
|---|
| TAR-T20130-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Elastatinal is an elastase inhibitor. It is found in culture filtrates of various species of actinomyces.
CAS:
51798-45-9
Formula:
C21H36N8O7
Molecular Weight:
512.568
Purity:
0.98
SMILES:
CC(C)C[C@H](NC(=O)N[C@@H]([C@@H]1CCNC(N)=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C=O)C(O)=O
References
1. Maxson T, Tietz JI, Hudson GA, Guo XR, Tai HC, Mitchell DA. Targeting Reactive Carbonyls for Identifying Natural Products and Their Biosynthetic Origins. J Am Chem Soc. 2016 Nov 23;138(46):15157-15166. Epub 2016 Nov 14. PubMed PMID: 27797509; PubMed Central PMCID: PMC5148692.
2. Barros SC, Martins JA, Marcos JC, Cavaco-Paulo A. Characterization of potential elastase inhibitor-peptides regulated by a molecular switch for wound dressings applications. Enzyme Microb Technol. 2012 Feb 10;50(2):107-14. doi: 10.1016/j.enzmictec.2011.10.006. Epub 2011 Nov 7. PubMed PMID: 22226196.
3. Sun T, Zhang S, Ji G. Identification and expression of an elastase homologue in Branchiostoma belcheri with implications to the origin of vertebrate pancreas. Mol Biol Rep. 2010 Oct;37(7):3303-9. doi: 10.1007/s11033-009-9916-5. Epub 2009 Nov 12. PubMed PMID: 19908163.
4. Ferreira GA, Magliano AC, Pral EM, Alfieri SC. Elastase secretion in Acanthamoeba polyphaga. Acta Trop. 2009 Nov;112(2):156-63. doi: 10.1016/j.actatropica.2009.07.015. Epub 2009 Jul 24. PubMed PMID: 19632188.