Amfenac sodium
| Code | Size | Price |
|---|
| TAR-T20197-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Amfenac is a nonsteroidal anti-inflammatory drug. Amfenac also has acetic acid moiety.
CAS:
61941-56-8
Formula:
C15H12NNaO3
Molecular Weight:
277.255
Purity:
0.98
SMILES:
[Na+].Nc1c(CC([O-])=O)cccc1C(=O)c1ccccc1
References
1. Sheppard JD, Cockrum PC, Justice A, Jasek MC. In Vivo Pharmacokinetics of Bromfenac Ophthalmic Solution 0.075%, Bromfenac Ophthalmic Solution 0.07%, and Nepafenac/Amfenac Ophthalmic Suspension 0.3% in Rabbits. Ophthalmol Ther. 2018 May 14. doi: 10.1007/s40123-018-0130-1. [Epub ahead of print] PubMed PMID: 29761367.
2. Acar U, Acar DE, Tanriverdi C, Acar M, Ozdemir O, Erikci A, Ornek F. Prostaglandin E(2) Levels of Aqueous and Vitreous Humor in Ketorolac 0.4% and Nepafenac 0.1% Administered Healthy Rabbits. Ocul Immunol Inflamm. 2017 Jun;25(3):323-327. doi: 10.3109/09273948.2015.1116587. Epub 2016 Jan 14. PubMed PMID: 26765265.
3. Chastain JE, Sanders ME, Curtis MA, Chemuturi NV, Gadd ME, Kapin MA, Markwardt KL, Dahlin DC. Distribution of topical ocular nepafenac and its active metabolite amfenac to the posterior segment of the eye. Exp Eye Res. 2016 Apr;145:58-67. doi: 10.1016/j.exer.2015.10.009. Epub 2015 Oct 22. PubMed PMID: 26474497.
4. Kida T, Kozai S, Takahashi H, Isaka M, Tokushige H, Sakamoto T. Pharmacokinetics and efficacy of topically applied nonsteroidal anti-inflammatory drugs in retinochoroidal tissues in rabbits. PLoS One. 2014 May 5;9(5):e96481. doi: 10.1371/journal.pone.0096481. eCollection 2014. PubMed PMID: 24796327; PubMed Central PMCID: PMC4010472.