AG-1478 hydrochloride
| Code | Size | Price |
|---|
| TAR-T20199-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
AG1478 HCl is an epidermal growth factor receptor protein inhibitor.
CAS:
170449-18-0
Formula:
C16H15Cl2N3O2
Molecular Weight:
352.22
Purity:
0.98
SMILES:
Cl.COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC
References
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2. Levitzki A. Tyrosine kinases as targets for cancer therapy. Eur J Cancer. 2002 Sep;38 Suppl 5:S11-8. Review. PubMed PMID: 12528768.
3. Bowers G, Reardon D, Hewitt T, Dent P, Mikkelsen RB, Valerie K, Lammering G, Amir C, Schmidt-Ullrich RK. The relative role of ErbB1-4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells. Oncogene. 2001 Mar 15;20(11):1388-97. Review. Erratum in: Oncogene 2001 Jun 28;20(29):3927. PubMed PMID: 11313882.
4. Nagane M, Lin H, Cavenee WK, Huang HJ. Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implications. Cancer Lett. 2001 Jan;162 Suppl:S17-S21. Review. PubMed PMID: 11164186.