Dibenzalacetone
| Code | Size | Price |
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| TAR-T20303-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Dibenzylideneacetone is a synthetic curcumin analog. It leads to apoptotic cell death in Leishmania donovani.
CAS:
538-58-9
Formula:
C17H14O
Molecular Weight:
234.3
Purity:
0.98
SMILES:
O=C(/C=C/C1=CC=CC=C1)/C=C/C2=CC=CC=C2
References
1. Chauhan IS, SubbaRao G, Shankar J, Chauhan LKS, Kapadia GJ, Singh N. Chemoprevention of Leishmaniasis: In vitro antiparasitic activity of dibenzalacetone, a synthetic curcumin analog leads to apoptotic cell death in Leishmania donovani. Parasitol Int. 2018 Jun 15. pii: S1383-5769(18)30035-7. doi: 10.1016/j.parint.2018.06.004. [Epub ahead of print] PubMed PMID: 29913255.
2. Dohutia C, Chetia D, Gogoi K, Sarma K. Design, in silico and in vitro evaluation of curcumin analogues against Plasmodium falciparum. Exp Parasitol. 2017 Apr;175:51-58. doi: 10.1016/j.exppara.2017.02.006. Epub 2017 Feb 7. PubMed PMID: 28188731.
3. El-Ablack FZ, Metwally MA, Khalil AM. Michael Reaction of 3-aAryl-2,4-Dicarboethoxy-5-Hydroxy-5-Methylcyclohexanones. Org Chem Int. 2015 Sep 1;5(5):311-323. PubMed PMID: 26689538; PubMed Central PMCID: PMC4681101.
4. Sedighi V, Azerang P, Sardari S. Antimycobacterial evaluation of novel [4,5-dihydro-1H-pyrazole-1-carbonyl]pyridine derivatives synthesized by microwave-mediated Michael addition. Drug Test Anal. 2015 Jun;7(6):550-4. doi: 10.1002/dta.1712. Epub 2014 Sep 14. PubMed PMID: 25219796.