Levoleucovorin disodium

TargetMol
Product Code: TAR-T20337
Supplier: TargetMol
CodeSizePrice
TAR-T20337-5mg5mg£850.00
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Quantity:
TAR-T20337-50mg50mg£1,661.00
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Quantity:
TAR-T20337-100mg100mg£2,079.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Levoleucovorin disodium is the sodium salt of the enantiomerically active form of Folinic Acid.
CAS:
163254-40-8
Formula:
C20H21N7Na2O7
Molecular Weight:
517.41
Purity:
0.98
SMILES:
[Na+].[Na+].Nc1nc2NCC(CNc3ccc(cc3)C(=O)NC(CCC([O-])=O)C([O-])=O)N(C=O)c2c(=O)[nH]1

References

1. Mofidifar S, Sohraby F, Bagheri M, Aryapour H. Repurposing existing drugs for new AMPK activators as a strategy to extend lifespan: a computer-aided drug discovery study. Biogerontology. 2018 Apr;19(2):133-143. doi: 10.1007/s10522-018-9744-x. Epub 2018 Jan 15. PubMed PMID: 29335817. 2. Muto O, Munakata M, Yamagata K, Masuda A, Kotanagi K, Kichiraku T, Satoyoshi R, Kudoh K, Sawada T, Miyazawa H, Ouchi S, Kotanagi H, Sakata Y. Successful Treatment with 5-fluorouracil and Levofolinate Calcium in Advanced Gastric Cancer Patient with Disseminated Intravascular Coagulation. Gan To Kagaku Ryoho. 2017 Oct;44(10):867-869. PubMed PMID: 29066681. 3. Costa T, Nu?ez J, Felismino T, Boente L, Mello C. REOX: Evaluation of the Efficacy of Retreatment With an Oxaliplatin-containing Regimen in Metastatic Colorectal Cancer: A Retrospective Single-center Study. Clin Colorectal Cancer. 2017 Dec;16(4):316-323. doi: 10.1016/j.clcc.2017.03.002. Epub 2017 Mar 16. PubMed PMID: 28392022. 4. Zhao R, Aluri S, Goldman ID. The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption. Mol Aspects Med. 2017 Feb;53:57-72. doi: 10.1016/j.mam.2016.09.002. Epub 2016 Sep 21. Review. PubMed PMID: 27664775; PubMed Central PMCID: PMC5253092.