Inotodiol
| Code | Size | Price |
|---|
| TAR-T20613-5mg | 5mg | £837.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Inotodiol is an included triterpenoid with a significant effect of anti-tumor.
CAS:
35963-37-2
Formula:
C30H48O3
Molecular Weight:
456.711
Purity:
0.98
SMILES:
[H][C@@]12CC(=O)C3=C(CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)C(O)CC=C(C)C)[C@@]1(C)CC[C@H](O)C2(C)C
References
1. Zhao LW, Zhong XH, Yang SY, Zhang YZ, Yang NJ. Inotodiol inhabits proliferation and induces apoptosis through modulating expression of cyclinE, p27, bcl-2, and bax in human cervical cancer HeLa cells. Asian Pac J Cancer Prev. 2014;15(7):3195-9. PubMed PMID: 24815470.
2. Du D, Zhu F, Chen X, Ju X, Feng Y, Qi LW, Jiang J. Rapid isolation and purification of inotodiol and trametenolic acid from Inonotus obliquus by high-speed counter-current chromatography with evaporative light scatting detection. Phytochem Anal. 2011 Sep-Oct;22(5):419-23. doi: 10.1002/pca.1297. Epub 2011 Mar 24. PubMed PMID: 21433158.
3. Nomura M, Takahashi T, Uesugi A, Tanaka R, Kobayashi S. Inotodiol, a lanostane triterpenoid, from Inonotus obliquus inhibits cell proliferation through caspase-3-dependent apoptosis. Anticancer Res. 2008 Sep-Oct;28(5A):2691-6. PubMed PMID: 19035296.
4. Ying YM, Zhang LY, Zhang X, Bai HB, Liang DE, Ma LF, Shan WG, Zhan ZJ. Terpenoids with alpha-glucosidase inhibitory activity from the submerged culture of Inonotus obliquus. Phytochemistry. 2014 Dec;108:171-6. doi: 10.1016/j.phytochem.2014.09.022. Epub 2014 Oct 18. PubMed PMID: 25446238.