RK 397
| Code | Size | Price |
|---|
| TAR-T20686-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
RK 397 is an antibiotic of oxopentaene macrolide.
CAS:
154396-73-3
Formula:
C35H56O10
Molecular Weight:
636.823
Purity:
0.98
SMILES:
CCC1OC(=O)C=C/C=CC=C/C=CC=C/CC(O)C(C)C(O)CC(O)CC(O)CC(O)CC(O)CC(O)CC(O)C=C/C1C
References
1. Burova SA, McDonald FE. Total synthesis of the polyene-polyol macrolide RK-397, featuring cross-couplings of alkynylepoxide modules. J Am Chem Soc. 2004 Mar 3;126(8):2495-500. PubMed PMID: 14982459.
2. Kobinata K, Koshino H, Kudo T, Isono K, Osada H. RK-397, a new oxo pentaene antibiotic. J Antibiot (Tokyo). 1993 Oct;46(10):1616-8. PubMed PMID: 8244892.
3. Denmark SE, Fujimori S. Total synthesis of RK-397. J Am Chem Soc. 2005 Jun 29;127(25):8971-3. PubMed PMID: 15969572.
4. Guo H, Mortensen MS, O'Doherty GA. Formal total synthesis of RK-397 via an asymmetric hydration and iterative allylation strategy. Org Lett. 2008 Jul 17;10(14):3149-52. doi: 10.1021/ol801055b. Epub 2008 Jun 13. PubMed PMID: 18549226.