DIDS

TargetMol
Product Code: TAR-T20694
Supplier: TargetMol
CodeSizePrice
TAR-T20694-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
DIDS, an anion exchange inhibitor, acts by blocking reversibly and later irreversibly, exchangers such as chloride-bicarbonate exchanger. It is also a RAD51 inhibitor.
CAS:
53005-05-3
Formula:
C16H10N2O6S4
Molecular Weight:
454.5
Purity:
0.98
SMILES:
OS(=O)(=O)c1cc(ccc1C=Cc1ccc(cc1S(O)(=O)=O)N=C=S)N=C=S

References

1. Zhang Q, Jing H, Su HC. Recent Advances in DOCK8 Immunodeficiency Syndrome. J Clin Immunol. 2016 Jul;36(5):441-9. doi: 10.1007/s10875-016-0296-z. Epub 2016 May 20. Review. PubMed PMID: 27207373; PubMed Central PMCID: PMC4914394. 2. Thinnes FP. Opening up of plasmalemma type-1 VDAC to form apoptotic "find me signal" pathways is essential in early apoptosis - evidence from the pathogenesis of cystic fibrosis resulting from failure of apoptotic cell clearance followed by sterile inflammation. Mol Genet Metab. 2014 Apr;111(4):439-44. doi: 10.1016/j.ymgme.2014.02.001. Epub 2014 Feb 13. Review. PubMed PMID: 24613483. 3. DiNuzzo M, Mangia S, Maraviglia B, Giove F. Regulatory mechanisms for glycogenolysis and K+ uptake in brain astrocytes. Neurochem Int. 2013 Nov;63(5):458-64. doi: 10.1016/j.neuint.2013.08.004. Epub 2013 Aug 19. Review. PubMed PMID: 23968961; PubMed Central PMCID: PMC4082998. 4. Liu Z, Liu L, Zhang Z, Chen Z, Zhao B. Cholesterol-reducing agents for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev. 2013 Apr 30;(4):CD008184. doi: 10.1002/14651858.CD008184.pub2. Review. PubMed PMID: 23633351.