Trandolaprilat
| Code | Size | Price |
|---|
| TAR-T20758-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T20758-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T20758-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Trandolaprilat is an inhibitor of non-sulfhydryl angiotensin-converting enzyme.
CAS:
87679-71-8
Formula:
C22H30N2O5
Molecular Weight:
402.491
Purity:
0.98
SMILES:
[H][C@@]12C[C@H](N(C(=O)[C@H](C)N[C@@H](CCc3ccccc3)C(O)=O)[C@@]1([H])CCCC2)C(O)=O
References
1. Li X, Liu C, Wu M, Zhang H, Sun Y, Cheng L, Chen H, Liu C, Yang L, Zhang Q, Cao Y, Gu J, Ding Y. Pharmacokinetics, Pharmacodynamics, and Tolerability of Single and Multiple Doses of Trandolapril, an Effective Angiotensin-Converting Enzyme Inhibitor, in Healthy Chinese Subjects. Eur J Drug Metab Pharmacokinet. 2016 Aug;41(4):373-84. doi: 10.1007/s13318-015-0277-2. PubMed PMID: 25864194.
2. Nirogi RV, Kandikere VN, Shrivastava W, Mudigonda K. Quantification of trandolapril and its metabolite trandolaprilat in human plasma by liquid chromatography/tandem mass spectrometry using solid-phase extraction. Rapid Commun Mass Spectrom. 2006;20(24):3709-16. PubMed PMID: 17117442.
3. Vidal M, Joly G, Mombouli JV, Boulanger CM, Vanhoutte PM. The endothelium and vascular effects of the ACE inhibitor trandolaprilat. J Cardiovasc Pharmacol. 1994;23 Suppl 4:S1-5. PubMed PMID: 7527094.
4. Tanonaka K, Kamiyama T, Takezono A, Sakai K, Takeo S. Beneficial effects of angiotensin I converting enzyme inhibitor on post-ischemic contractile function of perfused rat heart. J Mol Cell Cardiol. 1996 Aug;28(8):1659-70. PubMed PMID: 8877776.